Bruce is Chairman of the Department of Neurosciences at the Lerner Research Institute, Cleveland Clinic, Professor of Neurosciences at Case Western Reserve University and a fellow of the American Association for the Advancement of Science (AAAS). He joined the Cleveland Clinic as Chairman of the Department of Neurosciences in 1994. His research investigates the cause of neurological disability in multiple sclerosis patients, cellular mechanism of brain repair in neurodegenerative diseases, and the molecular biology of myelination in the central and peripheral nervous systems.  He is internationally known for his work on mechanisms of neurodegeneration and repair in multiple sclerosis and has published over 240 peer-reviewed articles and over 30 book chapters. Bruce is a member of the advisory board of major biotech companies, the National Institutes of Health and the National Multiple Sclerosis Society. He is active in organizing national and international conferences related to Neurodegenerative diseases.

Bruce is the recipient of the Jordi Folch-Pi Award, the Award of the American Society of Neurochemistry, The Weil Award from the American Association of Neuropathologists, the Harry Weaver Neuroscience Scholar Award from the National Multiple Sclerosis Society (NMSS), the Jacob Javits Award in Neuroscience from the National Institute of Neurological Disorders and Stroke, the John Dystel Prize for MS Research from the American Academy of Neurology and the National Multiple Sclerosis Society, the Scientific Achievement Award in Basic Science and the Award for Excellence in Science from the Cleveland Clinic.

He received his PhD from Loyola University Stritch School of Medicine in Chicago, IL and postdoctoral training at the National Institutes of Health (NIH), Bethesda, MD. He then was appointed Assistant and subsequently Associate Professor of Neurology at the Johns Hopkins University School of Medicine in Baltimore. 

Doug is a neurologist and neuroscientist with over 120 publications in medical journals. He received his MD and PhD degree in Biochemistry and Molecular biology from Jefferson Medical College and his MBA from Princeton.

Prior to joining Disarm, Todd held positions at Alkermes and Boehringer-Ingelheim. Most recently he led a medicinal chemistry effort that delivered a drug candidate to proceed into clinical trials. He contributed to the molecular discovery and lead optimization of several other development candidates for immunology, inflammation and cardiometabolic indications. He is the author of over 30 patents and peer-reviewed publications.

Todd earned his PhD in organic chemistry at the University of Pittsburgh and was an NIH postdoctoral fellow with Amos B. Smith, III at the University of Pennsylvania.